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Meeting of the Princeton ACS Sectio

Wednesday, September 13, 2023

Daniel Lee

Lead Scientist, R&D, International Flavors and Fragrances, Inc.

“Flavor Emulsion Fabricated with Lysolecithin for Clear Beverages”

Frick Chemistry Laboratory, Princeton University

Mixer 6:30 pm; Lecture 7:00 pm 

Abstract: Flavor extracts of essential oils are frequently used to create optically clear or transparent ready to drink beverages, however, they often lack balanced flavor profiles and mouthfeel which provide the rich-tasting experience consumers are looking for.  A shelf-stable flavor emulsion comprising patented lysolecithin as part of the emulsifier system was designed to deliver full flavorings without compromising the visual clarity of a liquid beverage.  Phospholipid composition of the lysolecithin was determined by 31P-NMR analysis, which was compared with select commercial lecithin products to better understand differences of their functionality.  Performance assessment was carried out by sensory evaluation of the beverage as well as characterizations of the emulsion at zero time and in storage.

Biography: Daniel Lee is a Lead Scientist at International Flavors and Fragrances in Research & Development (IFF R&D), specializing in innovative flavor delivery systems for over 25 years.  During his tenure at IFF, he led multiple projects that resulted in commercialized technologies for food and beverage applications.  He was one of the pioneers who developed a controlled-release scent technology for the successful commercial application to numerous consumer products.  Daniel possesses a broad working knowledge of ingredient functionality to design specialized delivery system matrices for optimal performance.  He is a co-inventor on 13 U.S. and international patents.  Daniel earned his M.S. and Ph.D. degrees in Food Science & Technology from Texas A&M University and University of Minnesota, respectively.  Prior to his employment at IFF R&D, he worked in Friskies R&D, Nestle, to develop novel reaction flavors that landed significant commercial sales.

Registration: There is no fee to attend the meeting but registration is requested. To register go to https://www.princeton-acs.org/events/september13-meeting-xgw3p  

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PACS Fall Organic Chemistry Symposium

The 45th annual Princeton ACS Fall Organic Chemistry Symposium will be held on October 12th, 2023 at the Ernest Mario School of Pharmacy at Rutgers University in Piscataway, New Jersey.  Mark your calendars for a great day of science and discussion.  Speakers include Vy Dong (UC-Irvine), Tim Cernak (University of Michigan.), Daniel Nomura (UC-Berkley), and Scott Denmark (University of Illinois Urbana-Champaign.) 

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Chemagination at Princeton is “Full STEAM Ahead” for Local High Schools

By Barbara Ameer, Chemagination Committee Chair and Local Section Competition Coordinator 

Congratulations to participants in our June local section Chemagination competition, which was asynchronous/remote for the fourth consecutive year in its 21-year history.

Teams consisting of 2 or 3 high school science students tackled the question: How might chemistry be used along with allied fields like biology to improve our lives 25 years in the future? After selecting one of five categories of chemistry, students researched then wrote their feature story including graphics, a timeline and cover art for the high school chemistry magazine ChemMatters, as if it were 2048.

Over the past few years, the remotely-held contest has been very successful. In both 2022 and 2023, teachers from 5 schools guided about 120 students through the novel activity, reinforcing their interest in our novel science competition.

Of the 38 teams entering 2023 Chemagination at Princeton, the winners were:

Alternate Energy Sources

First place (tie) Team #AE2 Akshath Sarukkai and Anton Misirpashayev, Plasma Catalysis in Ammonia Synthesis, West Windsor-Plainsboro High School-South (WWPHS-S)

First place (tie) Team #AE7 Richard Aerath, Rishi Bajaj and Nishant Ganesan, The Revolutionary Capabilities of Hydrogen Fuel Cells, WWPHS-S

Second place Team #AE3 Matthew Canales, Tyler Cimler and Aprameya Kannan, Energy Evolution: Solid-State Batteries, Hightstown High School

Third place Team #AE4 Jagan Rajeev and Manan Patel, The Secret Behind the Sparkle, Hillsborough HS

Environment 

First place Team #E3: Paul Li and Leo Li, Mineral “Magic:” Revolutionizing Carbon Sequestration, WWPHS-S

Second place Team #E2: Nabeeha Anis and Anjali Ravikanti, Converting Fertilizer Runoff into Eco-friendly Products, WWPHS-S

Third place Team #E5: Adhithi Rajesh and Victor Ma, Ocean Acidification: Neutralizing the Effects of Carbon Emissions, Hillsborough High School

Medicine/Health

First place Team #M3: Princie Shah and Arishtha Dey, One Print Away: The Future of Osteoarthritis, WWPHS-S

 Second place Team #M6: Nivedha Sundarrajan and Roshne Nagrajan, Neurotoxic Peptide Hillsborough High School

Third place Team #M2: Nandita Dandamudi and Ishaan Nittukandi, Revolutionary Cure for Alzheimer’s Disease Using Enzymes and Coral, WWPHS-S

New Materials

First place Team #NM2: Brayden Lee and Revin Aloysius, TaCo2Te2 – Spinning into a New Solution in Memory, WWPHS-S

Second place Team #NM6: Anna Fenchenko and Kevin Zhang, Construction of Space Elevators Using Carbon Nanotubes and Self-healing Materials, Princeton International School of Mathematics and Science

Third place Team #NM3: Pratham Satti, Shirish Naidu and Krrish Madavarapu, The Next Generation Prosthetic Materials, WWPHS-S

 Proteins/Protein Chemistry

First place Team #P6: Tisha Jasani, Jana Mehanna and Prisha Agrawal, Managing Diabetic Dementia, WWPHS-S

Second place Team #P3: Vishnu Bharadwaaj and Kyle Colipano, “Save"-ry Sugars: Glycoprotein Therapeutics, Hillsborough High School

Third place Team #P2: Audrey Fu, Leeann Shaw and Locke Cai, Photosynthesis 2.0, WWPHS-S

 Other

Honorable Mention Team #AE1: Kamila Zuba and Kaylee Gusciora, Bioleaf Energy Resolution, Wallington Junior/Senior High School

First-place teams (or second- or third-place teams as alternates) are eligible to participate in the ACS regional MARM Chemagination, to be held in central Pennsylvania in early June 2024.

We appreciate the expertise of the 15-membered judging team. We enjoy a good relationship with our New Jersey high school chemistry teacher-mentors. They include Kenneth Lisk, Hightstown HS, Karen Randazzo, Hillsborough HS, Barbara Safira, Wallington Jr/Sr HS, Cindy Jaworsky and Karel Villanueva, West Windsor-Plainsboro HS-S, and Randy A. Weintraub, chemistry teacher at Princeton International School of Mathematics and Science, who also coordinated the 5 judging teams.                                   

 

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MARM 2023 Poster Session

 

Barbara Ameer, Chemagination Committee Chair and Local Section Competition Coordinator, presented a poster at MARM 2023 on June 9 at the City University of New York and communicated to attendees how the pandemic spurred positive change in our local section Chemagination competition.

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2023 Alyea Award Winners 

The namesake of this award, Hubert Newcombe Alyea, was a Professor of Chemistry at Princeton University who was world renowned for his scientific demonstrations, his enthusiasm, and his love of scientific discovery. Each year Princeton University and ACS Local Section jointly present Awards to students from local schools. Our Award Winners are selected based on their demonstrated enthusiasm for the study of science and as students who excels in chemistry and related scientific disciplines. The Award consists of a certificate and check for $125.

This year’s Awardees, listed below, were invited to attend Princeton University’s Chemistry Alumni Reunion Event on Friday, May 26 at which Prof. David MacMillan, 2021 Nobel Laureate in Chemistry, deliver a keynote on: “A Nobel Year: The Frenetic Life of a Nobel Laureate.” They were also invited to be recognized at our PACS Meeting on July 13.

Congratulations to our 2023 Hubert N. Alyea Award Winners:

-        Leslie Arellano, Trenton Central High School

-        Armaan Ahmed, Princeton High School

-        Brandon Feder, PRISMS

-        John Gunton, Lawrence High School

-        Danielle Im, Princeton Day School

-        Harshini Lakshminarayanan, WW-PHS-South

-        James McDonald, The Hun School of Princeton

-        Ria Patel, The Lawrenceville School

-        Arjun Sharma, Montgomery High School

-        Tyler Weniger, Nottingham High School

-        Matthew Yang, The Peddie School

 

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Princeton Section’s US National Chemistry Olympiad Awards Finalists

Danielle Jacobs, Trenton Section member, once again coordinated the Chemistry Olympiad program for both the Trenton and Princeton Sections.  Local exams took place this past March and those students that qualified went on to take the national exam in April.  This exam is comprised of multiple choice and problem-solving questions, and a lab practical. The top 50 test takers are designated with High Honors and the next 100 with Honors. This year’s finalists from the Princeton Section were recognized at the June 13th Meeting of the Princeton ACS.

The Finalists are:

Princeton High School: Teacher: Robert Corell

Armaan Ahmed - second year finalist in the national competition

Marc-Andre Morel - Received ‘Honors’

Princeton International School of Math & Science: Teacher: Steven Chen

Yiwei (David) Liang - Received ‘High Honors’ and was chosen for 2023 USNCO study camp; second year finalist in national competition

Junrui (Jonathan) Hai - Received ‘Honors’

Qixiang (Carnegie) Feng 

Stuart Country Day School: Teacher: Natalia Voicu

 Sarah Nagarkatti 

West Windsor Plainsboro High School South: Teacher: Cindy Jaworsky

Alexander Huang - Received ‘Honors’; second year finalist in national competition

Ethan Song - Received (‘High Honors’) and chosen for 2023 USNCO study camp; second year finalist in national competition 

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ACS 50/50/70 Year Members 

Each year, the ACS recognizes those members that have been members of the society for 50, 60 or 70 years.  Certificates are mailed to Local Sections for distribution.  This year, the Princeton Section recognized our 50/60/70 Year Members at our June13th meeting.  They are:

50 Year Members

Dr. Steven Bernasek

Dr. Edward Edelson

Mr. Dennis Kujawski

Dr. Paul Reider

Dr. Kathryn Wagner

Dr. Harold Weller

60 Year members

Dr. Michael Kaplan

70 Year Members

Dr. Henry Friedman

Dr. David Richman

Join in congratulating them on achieving this milestone! 

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Chemagination at MARM 2023

The Regional Chemagination competition took place on Saturday, June 10th at St. John’s University in conjunction with MARM 2023.  For this competition students must imagine that they are scientist living 25 years in the future and have made a discovery that has had a positive impact on people’s lives.  They must write an article describing the science and present that article on a poster and in interviews with judges. The articles are in one of four categories: Alternative Energy; Environment; Medicine/Health or New Materials.

This year a total of 16 teams competed, representing the Lehigh Valley, New York, North Jersey, Philadelphia, Princeton and Trenton ACS Sections. Each team was interviewed by two or three judges and First and Second Place winners were chosen in each category.

The teams from the Princeton and Trenton ACS Sections came away with two ‘First’s’ among a group of many strong teams.  Congratulations to:

First Place Alternative Energy – ‘Nuclear Fusion: Limitless Applications of Limitless Energy”, Ajay Desai, Atharva Katkar and Vinay Panchal, Hillsborough High School, Karen Randazzo, teacher, Princeton Section

First Place Environment - “Novel Black Carbon Filtration with Sonic Agglomeration and Nanofibers”, Sumedha Jayarman and Leo Li, West Windsor-Plainsboro High School South, Cindy Jaworski, teacher, Princeton Section

Congratulations also to the winners from the other Sections:

Alternative Energy Category

Second Place - “Seawater Powers the World: How thermonuclear energy helped replace fossil fuels with seawater”, Paolo Arcuri, Gianna Conte and Abigail Fearon, Fort Lee High School County Academies, Patricia Konstantinova, teacher, North Jersey Section

Environment Category

Second Place – “Harnessing Earth’s Natural Processes to Encourage Carbon Sequestration”, Noah Feigenbaum, Sergio Rosa and Avery Testa, South Side High School, Herb Weiss, teacher, New York Section

Medicine/ Health Category

First Place – “Ataraxia; the Solution to 'Space Insomnia”, Rayan Afzal, Jacob Park and Dylan Stone, Half Hollow Hills High School West, Christine Tjersland, teacher, New York Section

Second Place – “Bee Cancer Free (Curing 1 Illness at a Time with Melittin)”, Eugene Hwang, Joseph Kim and Chaemin Yeo, Fort Lee High School, Patricia Konstantinova, teacher, North Jersey Section

New Materials Category

First Place – “GemGuard Necklace”, Allyssa Rhianna Aquino, Meaghan Campbell and Catherine Purirojejananon, General Douglas MacArthur High School, David Friedman and Matthew Zausin, teachers, New York Section

Second Place – “PneumoPatch: A Revolutionary Nano-technology Approach to Reducing Pulmonary Fibrosis”. Michelle Cheon, Jiho Choi and Elizabeth Kam, Fort Lee High School, Patricia Konstantinova, teacher, North Jersey Section

Thank you to the students, parents, teachers, judges, contest organizers, St. John’s University graduate students and other volunteers who helped make MARM 2023 Chemagination a success!

 

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Other Local Events

 

Tuesday, June 27, 2023 - North Jersey Mass Spectrometry Discussion Group.

Venue: Somerville Elks Lodge 1068, 375 Union Avenue, Bridgewater, NJ 08807, phone: 908-707-1545

Registration is free.  To register and for meeting information go to  https://www.njacs.org/topical-groups/mass-spectrometry/register

Program:

5:30 PM    Social and Registration 
6:00 PM    Complimentary Dinner
6:55 PM    Welcome and Opening Remarks
7:05 PM    Speakers

SPEAKER: Srinivas Chakravartula, Ph.D, Mass Spectrometry Facility, Department of Chemistry and Chemical Biology.  Rutgers, The State University of New Jersey.

Title: Qualitative classification of tissue amyloidosis and subtyping by Laser Capture Microdissection (LMD) - LC-Mass spectrometry

Abstract: Amyloidosis is a disease characterized by abnormal deposits of insoluble polymeric protein fibrils in tissue and organs. Condition of deposition of amyloid tissue is known as Amyloidosis. In my talk I will demonstrate an approach which simplifies, analysis of these deposits by utilizing high flow liquid chromatography (LC) coupled to tandem mass spectrometry (MS/MS) of laser micro dissection (LMD) of Congo red +Ve amyloid deposits of formalin fixed paraffin embedded tissues (FFPE) from pathology preparations. The results presented  demonstrate the validity of shotgun faster proteomics for  precise and accurate identification and classification of amyloid subtypes that is practical for clinical application because of its shorter turnaround time bringing the state of the art pathological diagnosis of amyloidosis into the realm of routine surgical pathology practice to make the contribution of  mass spectrometry  even more powerful and meaningful for faster patient management decisions by clinicians and also for the effective treatment of amyloidosis. On the other hand, my LC-MS/MS assay is not just restricted for amyloid therapeutics but also opens the possibility of other tissues available to proteomics assays in studying other disease pathologies and for biomarker discoveries.

Speaker: Dr Gene Hall, PhD.   Professor of Analytical Chemistry Department of Chemistry and Chemical Biology Rutgers, The State University of New Jersey, Piscataway, NJ 08854

Title:  Use of ICP-MS to Determine Sources of Pb in NJ Homeowner’s Tap Water: A Case for Sequential Sampling

Abstract: We used an argon ion source to ionize the elements from Li to U in NJ homeowners, daycare centers, and elementary school tap water samples and plumbing materials. The ionized elements were sucked into a single quadrupole mass analyzer to determine concentrations and isotope ratios to determine Pb's source(s) in the various samples. The combined methods are called inductively coupled plasma mass spectrometry (ICP-MS).

This seminar will focus on using ICP-MS to determine Pb's source(s) in tap water samples collected from NJ homes, daycare centers, and elementary schools. A simple collect and inject workflow are established to rapidly assess the Pb sources using the unique stable Pb isotopes fingerprints related to their geological sources. Deviation from the EPA’s method of one liter first draw tap water to sequential sampling (50-ml intervals) revealed more information about Pb and other element sources in the water.

Stable Pb isotope ratio fingerprinting revealed that the major sources of Pb in tap water are derived from the Cu pipe, valves, water tank and fixtures. A false sense of security is developed when the Pb service line is replaced with polyvinyl chloride (PVC) in older homes constructed before 1986. 

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